Saturday, June 29, 2013

Medical Imaging: Illuminating the body


Hi,

My name is Franz Devantier, creator of this blog.  I am an Herbalist, who uses local and indigenous herbs when available, in preference to imported herbs.  Because Herbalists deal with living human beings, it is important to have an understanding of Anatomy and Physiology, as well as many other related subjects, such as How to grow old gracefully with Stem Cell Enhancers.

Medical Imaging: Illuminating the body
Before the 1950s, the X-Ray was the only way of extracting information about the internal state of the human body.  Unfortunately the images were a bit murky, but fairly useful.  For the rest of it, physicians had to examine the internal organs for evidence of disease by means of exploratory surgery.  Exploratory surgery subjected the patients to all the pain, shock and trauma of major surgery, but potentially without the benefit of any improvement to their condition.

An X-ray image is obtained by directing, X-rays, which are waves of a very short electromagnetic wavelength at the body.  The X-ray or radiograph is a shadowy negative of the internal structures of the body.  The denser structures absorb more X-rays, and so appear as lighter areas in the radiograph.  Hollow air containing structures and fat, absorb the X-rays to a lesser extent, and so appear as darker areas in the radiograph.  X-ray images can be viewed on a fluorescent screen or fluoroscope as they are being generated. 

X-rays are best at helping to visualize hard bony structures, and at locating abnormally dense structures, such as tumors and tuberculosis nodules in the lungs.

In the 1950s the use of nuclear medicine started.  Nuclear medicine uses radioisotopes to scan the body.  Also in this same period, we saw the advent of ultrasound techniques for scanning the human body.

 In the 1970s CT, PET, and MRI scanning techniques were introduced.  These new imaging techniques were able to reveal the structure of our insides.  Also using these techniques it was possible for the first time to get information about how the molecules were working inside our organs.

The best known of these three new techniques is the Computed Tomography (CT), which was originally known as Computerized Axial Tomography (CAT).  The CT is a refined version of the old X-ray equipment.  The patient is slowly moved through the doughnut shaped CT machine, while its X-ray tubes rotate around the body, and send beams from all directions to a specific level of the patient’s body.

At any point in time, the an-shaped beam of the CT machine is confined to  a slice of the human body, about as thick as a coin.  In conventional X-rays, there can be confusion because of overlapping structures.  In CT, the devices computer translates this information into a detailed cross sectional picture of each of the consecutive body regions scanned.  In other words the result could look similar to thin slices cut through the body for examination.

The CT scan has eliminated the need for exploratory surgery to a very large degree.  CT scans are the chosen method for evaluating most problems involving the brain.  CT is also fairly useful in examining the abdomen and certain skeletal problems.

Dynamic Spatial Reconstruction (DSR), is a special high speed CT device.  This technique provides   three dimensional images of the body organs, from any angle.  This technique also allows the movements and changes in the internal volumes of the organs to be scrutinized at normal body speed.  You can also see the internal body movements in slow motion, or examine them at a specific point in time.  DSR can be used to evaluate the lungs and other mobile organs.  The greatest value of DSR has been to visualize the heart beating, and blood flowing through the blood vessels; which allows heart defects, constricted blood vessels, and the status of a coronary heart bypass graft to be evaluated.

There is another computer assisted X-ray technique that is called Digital Subtraction Angiography (DSA).  Angiography refers to vessel pictures.  This technique will provide an unobstructed view of diseased blood vessels.  The principle is straight forward:  Conventional radiographs (X-rays) are taken before and after a contrast medium has been injected into an artery.  The computer subtracts the before image from the after image, which eliminates all the body structures that obscure the vessel.  The result is an unobstructed view of a diseased blood vessel.  DSA is very useful in identifying blockages of the arteries that supply the heart wall and the brain. 

So we can see that there have been a number very useful technologies based on X-rays.  In the same way nuclear medicine gave rise to a technology called Positron Emission Tomography (PET).

PET is a nuclear medical imaging technique that produces a three-dimensional image or picture of functional processes in the body.  The technology works by detecting pairs of gamma rays, that are emitted indirectly from a positron emitting radionuclide or tracer.  This tracer is introduced into the body on a chosen biologically active molecule.  Three dimensional images of the tracer concentration is created by computer programs.  In some machines a CT scan is run at the same time from the same machine.

One biologically active molecule that is chosen is an analogue of glucose.  The aim with this tracer is to indicate the tissue metabolic activity, based on the concentration of the regional glucose uptake.  This technology can be used to detect cancer metastasis, which is when cancer starts spreading to other areas in the body.  Besides glucose, there are other radiotracers that can be used to study many types of molecules and imaging of tissue concentrations.

The gamma ray is indicated by that funny looking “y” symbol.  This technology can produce vivid coloured pictures of the brains chemical activities.  PET has been very useful in studying brain activity in Alzheimer’s disease, and Epilepsy.  Visualizations of which part of the brain is active during talking, listening, problem solving etc, and be created with PET.  Before PET this would not have been possible.

My favourite imaging technology is Sonography or Ultrasound Imaging.  Firstly Sonography equipment is inexpensive, when compared to the other technologies.  Secondly it is much safer when compared to X-ray or nuclear technology.  The high-frequency or ultrasound waves that are used, seem to be safer than the ionizing forms of radiation used in nuclear medicine, or the X-rays used in CT technology.

In Sonography, the body is probed with pulses of sound waves that are reflected and scattered by body tissues and result in echoes being formed.  A computer analyses these body echoes and creates or constructs visual images of the outlines of body organs.  Often a single hand held device can be used to emit the sounds and to pick up the echoes.  This device can be moved around the body, allowing sections to be scanned from many different body planes.

Sonography is relatively safe, and because of this it is the technique that is chosen for obstetrics.  It can be safely used to determine the fetal position and the age of the fetas, and other information about the fetas.  It is also used to locate the placenta.

On the negative side, sound waves have a very low penetrating power, and rapidly dissipate in air.  Because of this Sonography is of little use in studying the structures of the lungs, or those structures that are surrounded by bone, such as the brain and the spinal cord.   

Franz Devantier,
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